Nootropil: Advanced Cognitive Support for Enhanced Mental Performance
| Product dosage: 800mg | |||
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Synonyms
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Nootropil is a high-purity pharmaceutical-grade nootropic agent, classified as a racetam compound, specifically indicated for the management of cognitive disorders. Its primary active ingredient, piracetam, functions by modulating neurotransmission, enhancing neuronal membrane fluidity, and improving cerebral microcirculation. Clinically, it is utilized to support cognitive rehabilitation, improve memory recall, and facilitate mental clarity in indicated patient populations. Available by prescription, Nootropil represents a well-researched option within the spectrum of cognitive enhancers, backed by decades of clinical use and pharmacological study.
Features
- Active ingredient: Piracetam 800mg or 1200mg per tablet
- Pharmaceutical grade, manufactured under GMP conditions
- High bioavailability with rapid absorption
- Minimal protein binding, facilitating efficient blood-brain barrier penetration
- Long-established safety profile with extensive clinical documentation
- Available in multiple strengths for tailored dosing regimens
Benefits
- Enhances synaptic plasticity, supporting learning and memory consolidation
- Improves neuronal energy metabolism and oxygen utilization in the brain
- Supports recovery of cognitive function following neurological insult
- Aids in verbal fluency and information processing speed
- Reduces mental fatigue during prolonged cognitive tasks
- May support functional rehabilitation in age-related cognitive decline
Common use
Nootropil is primarily indicated for the management of cortical myoclonus, though it is extensively used off-label for cognitive enhancement and neuroprotection. It is commonly prescribed in cases of mild cognitive impairment, post-stroke recovery, and dyslexic syndromes in combination with other therapies. In clinical practice, it is also utilized to support cognitive function in elderly patients experiencing age-related memory decline. Its application extends to adjuvant therapy in vertigo and sickle cell anemia, owing to its rheological effects on red blood cells.
Dosage and direction
Dosage must be individualized based on therapeutic response and tolerability. For cognitive support in adults, the typical initial dosage is 1600mg daily, divided into two or three doses. This may be gradually increased to 4800mg daily based on clinical response. For cortical myoclonus, maintenance doses of 7200mg to 24000mg daily have been used under strict medical supervision. Tablets should be swallowed whole with water, preferably with meals to minimize potential gastrointestinal discomfort. Dosage adjustments are necessary in renal impairment. Treatment should not be discontinued abruptly.
Precautions
Renal function should be assessed before initiation and periodically during treatment, as piracetam is primarily excreted unchanged by the kidneys. Use with caution in patients with hemostatic disorders or those undergoing major surgery due to potential effects on platelet aggregation. Elderly patients may require dosage adjustments based on creatinine clearance. Patients should be monitored for signs of nervousness, anxiety, or sleep disturbances. Not recommended for use during pregnancy unless clearly necessary. Breastfeeding should be discontinued during treatment.
Contraindications
Hypersensitivity to piracetam or any excipients in the formulation. Severe renal impairment (creatinine clearance <20 mL/min). Patients with cerebral hemorrhage. Huntington’s chorea due to theoretical risk of exacerbating choreiform movements. Not indicated for children under 16 years of age except in specific pediatric neurological conditions under specialist supervision.
Possible side effects
Most adverse reactions are dose-dependent and reversible upon dosage reduction. Common side effects include nervousness (7.7%), weight gain (6.6%), and somnolence (3.8%). Gastrointestinal disturbances such as nausea, diarrhea, and abdominal pain occur in approximately 5% of patients. Less frequently reported effects include dizziness, insomnia, headache, and agitation. Rare cases of hypersensitivity reactions including rash, pruritus, and angioedema have been documented. Very rare reports of thrombophlebitis and coagulation disorders.
Drug interaction
May potentiate effects of anticoagulants and antiplatelet agents, requiring increased monitoring of coagulation parameters. Can enhance the effects of centrally acting drugs including antipsychotics, antidepressants, and anxiolytics. Concomitant use with thyroid hormones may increase irritability and confusion. Cholinergic drugs may demonstrate synergistic effects. No significant interactions with cytochrome P450 enzyme systems have been documented.
Missed dose
If a dose is missed, it should be taken as soon as remembered unless it is nearly time for the next scheduled dose. In that case, skip the missed dose and resume the regular dosing schedule. Do not double the dose to make up for a missed one. Maintaining consistent blood levels is important for optimal therapeutic effect, particularly in management of cortical myoclonus.
Overdose
Symptoms of overdose may include diarrhea, abdominal pain, and marked nervousness. In severe cases, hematological changes including leukopenia and thrombocytopenia have been reported. There is no specific antidote. Treatment should be symptomatic and supportive. Gastric lavage may be considered if ingestion was recent. Hemodialysis is effective in removing piracetam from the bloodstream, with clearance rates of approximately 50-60% over 4 hours.
Storage
Store at room temperature (15-30°C) in the original container, protected from light and moisture. Keep tightly closed and out of reach of children. Do not use after the expiration date printed on the packaging. Do not transfer to alternative containers as this may affect stability. Proper disposal of unused medication should follow local regulations for pharmaceutical waste.
Disclaimer
This information is provided for educational purposes only and does not constitute medical advice. Nootropil is a prescription medication and should only be used under the supervision of a qualified healthcare professional. Individual results may vary. Always consult with a physician before starting, changing, or discontinuing any medication. The full prescribing information should be consulted before use.
Reviews
Clinical studies demonstrate significant improvement in verbal learning and memory recall scores compared to placebo (p<0.01) in patients with age-associated memory impairment. In post-stroke rehabilitation trials, patients showed 34% greater improvement in cognitive function assessment scales versus standard care alone. Long-term observational studies indicate good tolerability with 78% of patients continuing therapy beyond 12 months. Specialist neurologists report particular efficacy in cortical myoclonus management, with 60% reduction in seizure frequency in responsive patients. Patient-reported outcomes highlight improved concentration and reduced mental fatigue in daily activities.